The English Premier League is back in business following its dark weekend as international qualification for the 2022 Fifa World Cup took over.
And there could be a homecoming in the offing at Old Trafford after the sensational re-signing of Cristiano Ronaldo by Manchester United from Juventus as the transfer deadline loomed.
Newcastle are the visitors on Saturday, as Ole Gunnar Solskjaer’s side set out to continue their unbeaten start to the new season.
Chelsea start the weekend on the same seven-point haul as United and they take on Aston Villa in the evening kick off at Stamford Bridge.
The sole Sunday game sees fellow hotshots Liverpool, also with two wins and a draw so far, travel across the Pennines to face the always intriguing challenge of a Leeds side under the charge of Marcelo Bielsa.
Arsenal have the perfect opportunity to end their miserable start to the campaign at the Emirates Stadium on Saturday.
Coach Mikel Arteta and his staff won’t dare to think what the reaction will be should they lose for a fourth straight match, with fellow pointless side Norwich the visitors.
It’s the complete opposite across north London, with Tottenham sitting pretty at the top of the embryonic EPL standings under new coach Nuno Espirito Santo.
Spurs pit their perfect record against Crystal Palace in a London derby at the Tottenham Hotspur Stadium on Saturday lunchtime, with three victories by the only goal already in the bag.
Leicester stand in the way of goal-hungry Manchester City, meanwhile, with the pair meeting at the King Power Stadium.
Wolves’ latest bid to get off the Premier League mark comes in the shape of a trip to Vicarage Road to play Watford, who picked up their three points on the opening day.
David Moyes looks to be putting together another eye-catching run with West Ham, following their European tilt last season.
The Hammers head to the south coast to tackle a Southampton side that are yet to win this season.
Brentford and Brighton complete the Saturday line up with their fixture in west London.
And there’s even some Monday night football to polish off the fourth round of action in the north west, with Everton welcoming Burnley to Goodison Park.
English Premier League predictions for 11 – 13 September
Prediction methodology explained: The expected win percentage is based off publicly available odds. For example, if a team?s odds are 2.30, the expected chance of winning is 43%. If the odds are 1.62 the expected chance of winning is 62% and so on. These are accurate at the time of writing but are subject to change. Where there is no value listed, the odds were not available at the time of writing.